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2021
   
114. Yu J, Cho E, Kwon H, Jeon J, Seong Sin J, Kwon Park J, Kim JS, Woong Choi J, Jin Park S, Jun M, Choon Lee Y, Hoon Ryu J, Lee J, Moon M, Lee S, Cho JH, Kim DH. Akt and calcium-permeable AMPA receptor are involved in the effect of pinoresinol on amyloid β-induced synaptic plasticity and memory deficits. Biochem Pharmacol. 2021 Feb 1;184:114366.
 
113. Hwang J, Youn K, Lim G, Lee J, Kim DH, Jun M. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. Nutrients. 2021 Jan 17;13(1):E254.
 
112. Seo HJ, Park JE, Choi SM, Kim T, Cho SH, Lee KH, Song WK, Song J, Jeong HS, Kim DH, Kim BC. Inhibitory Neural Network's Impairments at Hippocampal CA1 LTP in an Aged Transgenic Mouse Model of Alzheimer's Disease. Int J Mol Sci. 2021 Jan 12;22(2):E698.
 
2020
 
111. Yi JH, Kwon H, Cho E, Jeon J, Lee J, Lee YC, Cho JH, Jun M, Moon M, Ryu JH, Kim JS, Choi JW, Park SJ, Lee S, Kim DH. REDD1 Is Involved in Amyloid β-Induced Synaptic Dysfunction and Memory Impairment.Int J Mol Sci. 2020 Dec 13;21(24):E9482.
 

110. An SY, Lee M, Yoon HK, Abekura F, Kim KS, Kim DH, Kim HJ, Lee K, Kim CH, Lee YC. Regulation of human β-galactoside α2,6-sialyltransferase (hST6Gal I) gene expression during differentiation of human osteoblastic MG-63 cells. Glycoconj J. 2020 Dec;37(6):681-690.

 
109. Ji Y, Han J, Lee N, Yoon JH, Youn K, Ha HJ, Yoon E, Kim DH, Jun M. Neuroprotective Effects of Baicalein, Wogonin, and Oroxylin A on Amyloid Beta-Induced Toxicity via NF-κB/MAPK Pathway Modulation. Molecules. 2020 Nov 2;25(21):5087.
 
108. Kim YY, Yoon JH, Um JH, Jeong DJ, Shin DJ, Hong YB, Kim JK, Kim DH, Kim C, Chung CG, Lee SB, Koh H, Yun J. PINK1 alleviates thermal hypersensitivity in a paclitaxel-induced Drosophila model of peripheral neuropathy. PLoS One. 2020 Sep 17;15(9):e0239126. 
 
107. Kim DH, Kwon H, Choi JW, Shin CY, Cheong JH, Park SJ, Ryu JH. Roles of GABAA receptor α5 subunit on locomotion and working memory in transient forebrain ischemia in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Aug 30;102:109962.
 
106. Yi JH, Jeon J, Kwon H, Cho E, Yun J, Lee YC, Ryu JH, Park SJ, Cho JH, Kim DH. Rubrofusarin Attenuates Chronic Restraint Stress-Induced Depressive Symptoms. Int J Mol Sci. 2020 May 13;21(10):E3454. doi: 10.3390/ijms21103454.
 
105. Bae HJ, Kim J, Kim J, Goo N, Cai M, Cho K, Jung SY, Kwon H, Kim DH, Jang DS, Ryu JH. The effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice. Br J Pharmacol. 2020 Jul;177(14):3197-3209
 
104. Cai M, Jung I, Kwon H, Cho E, Jeon J, Yun J, Lee YC, Kim DH, Ryu JH. Spinosin Attenuates Alzheimer's Disease-Associated Synaptic Dysfunction via Regulation of Plasmin Activity.Biomol Ther (Seoul). 2020 Mar 1;28(2):131-136.
 
103. Deepa P, Bae HJ, Park HB, Kim SY, Kim S, Choi JW, Kim DH, Liu XQ, Ryu JH, Park SJ. Dracocephalum moldavica attenuates scopolamine-induced cognitive impairment through activation of hippocampal ERK-CREB signaling in mice.J Ethnopharmacol. 2020 May 10;253:112651.
 
102. Kwon H, Cho E, Jeon J, Kim KS, Jin YL, Lee YC, Yun J, Park SJ, Yi JH, Kim DH. Cryptotanshinone enhances neurite outgrowth and memory via extracellular signal-regulated kinase 1/2 signaling.Food Chem Toxicol. 2020 Feb;136:111011
 
101. Kim YY, Um JH, Yoon JH, Lee DY, Lee YJ, Kim DH, Park JI, Yun J. p53 regulates mitochondrial dynamics by inhibiting Drp1 translocation into mitochondria during cellular senescence. FASEB J. 2020 Feb;34(2):2451-2464
 
 
100. Oh J, Kim DH, Kim GY, Park EJ, Ryu JH, Jung JW, Park SJ, Kim GW, Lee S. Hydrangeae Dulcis Folium Attenuates Physical Stress by Supressing ACTH-Induced Cortisol in Zebrafish.Chin J Integr Med. 2020 Feb;26(2):130-137
 
2019
 
99. Han J, Ji Y, Youn K, Lim G, Lee J, Kim DH, Jun M. Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches.Nutrients. 2019 Nov 7;11(11). pii: E2694
 
98. Jeon J, Kwon H, Cho E, Kim KS, Yun J, Lee YC, Kim DH. The effect of coniferaldehyde on neurite outgrowth in neuroblastoma Neuro2a cells. Neurochem Int. 2019;131:104579
 
97. Bae HJ, Sowndhararajan K, Park HB, Kim SY, Kim S, Kim DH, Choi JW, Jang DS, Ryu JH, Park SJ. Danshensu attenuates scopolamine and amyloid-β-induced cognitive impairments through the activation of PKA-CREB signaling in mice. Neurochem Int. 2019 Dec;131:104537
 
96. Park HJ, Kwon H, Lee JH, Cho E, Lee YC, Moon M, Jun M, Kim DH, Jung JW. β-Amyrin Ameliorates Alzheimer's Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus.Biomol Ther (Seoul). 2020 Jan 1;28(1):74-82.
 
95. Lee J, Cho E, Kwon H, Jeon J, Jung CJ, Moon M, Jeon M, Lee YC, Kim DH, Jung JW. The fruit of Crataegus pinnatifida ameliorates memory deficits in β-amyloid protein-induced Alzheimer's disease mouse model. J Ethnopharmacol. 2019 Oct 28;243:112107
 
94. Cho E, Cai M, Kwon H, Jeon J, Moon M, Jun M, Lee YC, Yi JH, Ryu JH, Kim DH. Rubrofusarin inhibits Aβ aggregation and ameliorates memory loss in an Aβ-induced Alzheimer's disease-like mouse model. Food Chem Toxicol. 2019 Oct;132:110698
 
93. Kwon H, Cho E, Jeon J, Lee YC, Kim DH. Effect of an ethanol extract of Cassia Obtusifolia seeds on alcohol-induced memory impairment. J Life Sci. 2019;29(5):564~569.
 
92. ÀÌÁöÇý, ±èÇýÁ¤, ±èµ¿Çö, ½Å¹ü¿µ, Á¤Áö¿í. ¾Æ¹Ð·ÎÀÌµå º£Å¸·Î À¯¹ßÇÑ ¾ËÃ÷ÇÏÀ̸Ӻ´ ¸ðµ¨¿¡¼­ ½Å¼±ÃÊÀÇ ±â¾ï·Â °³¼± È¿°ú. ´ëÇѺ»ÃÊÇÐȸÁö, Á¦34±Ç Á¦3È£(2019³â 5¿ù) 1-7.
 
91. Yu J, Kwon H, Cho E, Jeon J, Kang RH, Youn K, Jun M, Lee YC, Ryu JH, Kim DH. The effects of pinoresinol on cholinergic dysfunction-induced memory impairments and synaptic plasticity in mice. Food Chem Toxicol. 2019 March;125:376-382.
 
90. Park HJ, Jung IH, Kwon H, Yu J, Jo E, Kim H, Park SJ, Lee YC, Kim DH, Ryu JH. The ethanol extract of Zizyphus jujuba var. spinosa seeds ameliorates the memory deficits in Alzheimer's disease model mice. J Ethnopharmacol. 2019 April 6;233:73-9  
   
2018  
   
89. Lee S, Youn K, Kim DH, Ahn MR, Yoon E, Kim OY, Jun M. Anti-Neuroinflammatory Property of Phlorotannins from Ecklonia cava on Aβ25-35-Induced Damage in PC12 Cells. Mar Drugs. 2018 Dec 22;17(1). pii: E7.
 
88. Lee M, Choi H, Kim KS, Kim DH, Kim CH, Lee YC. Curcumin Downregulates Human GM3 Synthase (hST3Gal V) Gene Expression with Autophagy Induction in Human Colon Carcinoma HCT116 Cells. Evid Based Complement Alternat Med. 2018 Nov 11;2018:6746412  
   
87. Yi JH, Kim DH, Piers TM, Kim SC, Whitcomb DJ, Regan P, Cho K. Postsynaptic p47phox regulates long-term depression in the hippocampus. Cell Discovery. 2018 Dec;4:44  
   
86. Zhang J, Ko SY, Liao Y, Kwon Y, Jeon SJ, Sohn A, Cheong JH, Kim DH, Ryu JH. Activation of the dopamine D1 receptor can extend long-term spatial memory persistence via PKA signaling in mice. Neurobiol Learn Mem. 2018 May 24. pii: S1074-7427(18)30127-8.  
   
85. Lee M, Kim KS, Fukushi A, Kim DH, Kim CH, Lee YC. Transcriptional Activation of Human GD3 Synthase (hST8Sia I) Gene in Curcumin-Induced Autophagy in A549 Human Lung Carcinoma Cells. Int J Mol Sci. 2018 Jul 2;19(7). pii: E1943.  
   
84. Lee J, Kwon H, Yu J, Cho E, Jeon J, Lee S, Ryu JH, Lee YC, Kim DH, Jung JW. The enhancing effect of Aubang Gahl Soo on the hippocampal synaptic plasticity and memory through enhancing cholinergic system in mice. J Ethnopharmacol. 2018 Oct;224:91-99.  
   
83. Yi JH, Zhang J, Ko SY, Kwon H, Jeon SJ, Park SJ, Jung J, Kim BC, Lee YC, Kim DH, Ryu JH. Fluoxetine Inhibits Natural Decay of Long-Term Memory via Akt/GSK-3β Signaling. Mol Neurobiol. 2018 Sep;55(9):7453-7462.  
   
82.Kwon H, Jung JW, Lww YC, Ryu JH, Kim DH. Neuroprotective effect of the ethanol extract of Artemisia capillaris on transient forebrain ischemia in mice via nicotinic cholinergic receptor. Chin J Nat Med. 2018 June;16(6):428-435  
   
81. Jeon SG, Kang M, Kim YS, Kim DH, Nam DW, Song EJ, Mook-Jung I, Moon M. Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice. Exp Mol Med. 2018 Mar 23;50(3):e461.  
   
80. Yi JH, Baek SJ, Heo S, Park HJ, Kwon H, Lee S, Jung J, Jeon SJ, Kim BC, Lee YC, Ryu JH, Kim DH. Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity. Neuropharmacology.2018 Jan;128:282-292  
   
79. Jung WY, Kim H, Jeon SJ, Park HJ, Choi HJ, Kim NJ, Kim DH, Jang DS, Ryu JH. Eclalbasaponin II Ameliorates the Cognitive Impairment Induced by Cholinergic Blockade in Mice. Neurochem Res. 2018 Feb;43(2):351-362  
   
2017  
   
78. Kwon H, Jung IH, Yi JH, Kim JH, Park JH, Lee S, Jung JW, Lee YC, Ryu JH, Kim DH. The Seed of Zizyphus jujuba var. spinosa Attenuates Alzheimer’s Disease-Associated Hippocampal Synaptic Deficits through BDNF/TrkB Signaling. Biol. Pharm. Bull. 2017;40(12):2096-2104..  
   
77. Park HJ, Kwon H, Lee S, Jung JW, Ryu JH, Jang DS, Lee YC, Kim DH. Echinocystic acid facilitates neurite outgrowth in neuroblastoma Neuro2a cells and enhances spatial memory in aged mice. Biol. Pharm. Bull. 2017;40(10):1724-1729.  
   
76. Jeon SJ, Kim B, Park HJ, Zhang J, Kwon Y, Kim DH, Ryu JH. The ameliorating effect of 1-palmitoyl-2-linoleoyl-3-acetylglycerol on scopolamine-induced memory impairment via acetylcholinesterase inhibition and LTP activation. Behav Brain Res. 2017 May 1;324:58-65  
   
75. Jo SY, Jung IH, Yi JH, Choi TJ, Lee S, Jung JW, Yun J, Lee YC, Ryu JH, Kim DH. Ethanol extract of the seed of Zizyphus jujuba var. spinosa potentiates hippocampal synaptic transmission through mitogen-activated protein kinase, adenylyl cyclase, and protein kinase A pathways. J Ethnopharmacol. 2017 Mar 22;200:16-21..  
   
74. Jeon SJ, Lee HJ, Lee HE, Park SJ, Gwon Y, Kim H, Zhang J, Shin CY, Kim DH, Ryu JH. Oleanolic acid ameliorates cognitive dysfunction caused by cholinergic blockade via TrkB-dependent BDNF signaling. Neuropharmacology. 2017 Feb;113(Pt A):100-109  
   
2016
 
73. Yoon HK, An HK, Ko MJ, Kim KS, Mun SW, Kim DH, Kim CM, Kim CH, Choi YW, Lee YC. Upregulation of Human ST8Sia VI (α2,8-Sialyltransferase) Gene Expression by Physcion in SK-N-BE(2)-C Human Neuroblastoma Cells. Int J Mol Sci. 2016 Aug 2;17(8). pii: E1246.
 
72. Huh S, Baek SJ, Lee KH, Whitcomb DJ, Jo J, Choi SM, Kim DH, Park MS, Lee KH, Kim BC. The reemergence of long-term potentiation in aged Alzheimer's disease mouse model. Sci Rep. 2016 Jul 5;6:29152
 
71. Jung WY, Kim H, Park HJ, Jeon SJ, Park HJ, Choi HJ, Kim NJ, Jang DS, Kim DH, Ryu JH. The ethanolic extract of the Eclipta prostrata L. ameliorates the cognitive impairment in mice induced by scopolamine. J Ethnopharmacol. 2016 Aug 22;190:165-73.
 
70. DH Kim, SM Choi, J Jho, M Park, J Kang, SJ Park, JH Ryu, J Jo, H H Kim, BC Kim. Infliximab ameliorates AD-associated object recognition memory impairment. Behav Brain Res. 2016 Sep 15;311:384-91.
 
69. HJ Park, S Lee, JW Jung, YC Lee, SM Choi, DH Kim. Salvia miltiorrhiza Bunge Blocks Ethanol-Induced Synaptic Dysfunction through Regulation of NMDA Receptor-Dependent Synaptic Transmission. Biomol Ther (Seoul). 2016 Jul 1;24(4):433-7.
 
68. Yi JH, Cho SY, Jeon SJ, Jung JW, Park MS, Kim DH, Ryu JH. Early immature neuronal death is partially involved in memory impairment induced by cerebral ischemia. Behav Brain Res. 2016 Jul 15;308:75-82.
 
67. Yi JH, Park HJ, Lee S, Jung JW, Kim BC, Lee YC, Ryu JH, Kim DH. Cassia obtusifolia seed ameliorates amyloid β-induced synaptic dysfunction through anti-inflammatory and Akt/GSK-3β pathways. J Ethnopharmacol. 2016 Feb 3;178:50-7.
 
66. Baik JS, Mun SW, Kim KS, Park SJ, Yoon HK, Kim DH, Park MK, Kim CH, Lee YC. Apoptotic Effects of Cordycepin through the Extrinsic Pathway and p38 MAPK Activation in Human Glioblastoma U87MG Cells.J Microbiol Biotechnol. 2016 Feb 28;26(2):309-14.
 
65. Yi JH, Park HJ, Kim BC, Kim DH, Ryu JH. Evidences of the role of the rodent hippocampus in the non-spatial recognition memory. Behav Brain Res.2016 Jan 15;297:141-9.

 

2015
 
64. Yoon HK, Lee JW, Kim KS, Mun SW, Kim DH, Kim HJ, Kim CH, Lee YC. Serum Deprivation-Induced Human GM3 Synthase (hST3Gal V) Gene Expression Is Mediated by Runx2 in Human Osteoblastic MG-63 Cells. Int J Mol Sci. 2015 Dec 29;17(1). pii: E35.
 
63. Yi JH, Park HJ, Beak SJ, Lee S, Jung JW, Kim BC, Ryu JH, Kim DH. Danggui-Jakyak-San enhances hippocampal long-term potentiation through the ERK/CREB/BDNF cascade.. J Ethnopharmacol. 2015 Dec 4;175:481-489
 
62. Kim DH, Moon EY, Yi JH, Lee HE, Park SJ, Ryu YK, Kim HC, Lee S, Ryu JH. Peptide fragment of thymosin β4 increases hippocampal neurogenesis and facilitates spatial memory. Neuroscience. 2015 Dec 3;310:51-62.
 
61. Cho E, Kim DH, Hur YN, Whitcomb DJ, Regan P, Hong JH, Kim H, Ho Suh Y, Cho K, Park M. Cyclin Y inhibits plasticity-induced AMPA receptor exocytosis and LTP. Sci Rep. 2015 Jul 29;5:12624. doi: 10.1038/srep12624.
 
60. Whitcomb DJ, Hogg EL, Regan P, Piers T, Narayan P, Whitehead G, Winters BL, Kim DH, Kim E, St George-Hyslop P, Klenerman D, Collingridge GL, Jo J, Cho K. Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus. Sci Rep. 2015 Jun 9;5:10934
 
59. Regan P, Piers T, Yi JH, Kim DH, Huh S, Park SJ, Ryu JH, Whitcomb DJ, Cho K. Tau Phosphorylation at Serine 396 Residue Is Required for Hippocampal LTD. J Neurosci. 2015 Mar 25;35(12):4804-12.
 
58. Park HJ, Lee S, Jung JW, Kim BC, Ryu JH, Kim DH. Glucocorticoid- and long-term stress-induced aberrant synaptic plasticity are mediated by activation of the glucocorticoid receptor. Arch Pharm Res. 2015 Jun;38(6):1204-12.
 
57. Oh WB, Oh JY, Kim DH, Jung JW, Lee SH. Effect of the ethanolic extract of cactus pear (Opuntiaficus-indica) fruit on net handling stress in zebrafish. Kor. J. Herbology 2015 Jan;30(1):43-49.
 
56. Kim DH, Lee HE, Kwon KJ, Park SJ, Heo H, Lee Y, Choi JW, Shin CY, Ryu JH. Early immature neuronal death initiates cerebral ischemia-induced neurogenesis in the dentate gyrus. Neuroscience. 2015 Jan 22;284:42–54.
 
2014
 

55. Kim DH, Lee Y, Lee HE, Park SJ, Jeon SJ, Jeon SJ, Cheong JH, Shin CY, Son KH, Ryu JH. Oroxylin A enhances memory consolidation through the brain-derived neurotrophic factor in mice. Brain Res Bull. 2014 Sep 16;108C:67-73.

 
54. Song MD, Kim DH, Kim JM, Lee HE, Park SJ, Ryu JH, Lew JH. Danggui-Jakyak-San ameliorates memory impairment and increase neurogenesis induced by transient forebrain ischemia in mice. BMC Complement Altern Med. 2013 Nov 22;13:324
 
53. Kim JM, Kim DH, Lee Y, Park SJ, Ryu JH. Distinct roles of the hippocampus and perirhinal cortex in GABAA receptor blockade-induced enhancement of object recognition memory. Brain Res. 2014 Mar 13;1552:17-25
 
52. Narayan P, Holmstrom KM, Kim DH, Whitcomb DJ, Wilson MR, St George-Hyslop P, Wood NW, Dobson CM, Cho K, Abramov AY, Klenerman D. Rare individual amyloid-¥â oligomers act on astrocytes to initiate neuronal damage. Biochemistry. 2014 Apr 22;53(15):2442-53.
 
2013
 
51. Whitehead G, Jo J, Hogg EL, Piers T, Kim DH, Seaton G, Seok H, Bru-Mercier G, Son GH, Regan P, Hildebrandt L, Waite E, Kim BC, Kerrigan TL, Kim K, Whitcomb DJ, Collingridge GL, Lightman SL, Cho K. Acute stress causes rapid synaptic insertion of Ca2+-permeable AMPA receptors to facilitate long-term potentiation in the hippocampus. Brain. 2013 Dec;136(Pt 12):3753-65
 
50. Lee HE, Lee SY, Kim JS, Park SJ, Kim JM, Lee YW, Jung JM, Kim DH, Shin BY, Jang DS, Kang SS, Ryu JH. Ethanolic Extract of the Seed of Zizyphus jujuba var. spinosa Ameliorates Cognitive Impairment Induced by Cholinergic Blockade in Mice. Biomol Ther (Seoul). 2013 Jul 30;21(4):299-306
 
49. Liu X, Hong SI, Park SJ, Dela Pena JB, Che H, Yoon SY, Kim DH, Kim JM, Cai M, Risbrough V, Geyer MA, Shin CY, Cheong JH, Park H, Lew JH, Ryu JH. The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice. Arch Pharm Res. 2013 Jul;36(7):854-63.
 
48. Li E, Chung H, Kim Y, Kim DH, Ryu JH, Sato T, Kojima M, Park S. Ghrelin directly stimulates adult hippocampal neurogenesis: implications for learning and memory. Endocr J. 2013;60(6):781-9.
 
47. Oh SR, Kim SJ, Kim DH, Ryu JH, Ahn EM, Jung JW. Angelica keiskei ameliorates scopolamine-induced memory impairments in mice. Biol Pharm Bull. 2013;36(1):82-8.
 
46. Lee YW, Kim DH, Jeon SJ, Park SJ, Kim JM, Jung JM, Lee HE, Bae SG, Oh HK, Son KH, Ryu JH. Neuroprotective effects of salvianolic acid B on an A¥â25-35 peptide-induced mouse model of Alzheimer's disease. Eur J Pharmacol. 2013 Mar 15;704(1-3):70-7
 
45. Lee S, Kim DH, Lee JH, Ko ES, Oh WB, Seo YT, Jang YP, Ryu JH, Jung JW. Involvement of histaminergic system in the anxiolytic-like activities of Morus alba leaves in mice. Biol Pharm Bull. 2013;36(11):1692-9.
 
2012
 
44. Lee HE, Kim DH, Park SJ, Kim JM, Lee YW, Jung JM, Lee CH, Hong JG, Liu X, Cai M, Park KJ, Jang DS, Ryu JH. Neuroprotective effect of sinapic acid in a mouse model of amyloid ¥â(1-42) protein-induced Alzheimer's disease. Pharmacol Biochem Behav. 2012 Dec;103(2):260-6.
 
43. Park HJ, Kim DH, Park SJ, Kim JM, Ryu JH. Ginseng in traditional herbal prescriptions. J Ginseng Res. 2012 Jul;36(3):225-41
 

42. Kim DH, Kim JM, Park SJ, Lee S, Shin CY, Cheong JH, Ryu JH. Hippocampal extracellular signal-regulated kinase signaling has a role in passive avoidance memory retrieval induced by GABAA Receptor modulation in mice. Neuropsychopharmacology. 2012Apr;37(5):1234-44.

 

41. Liu X, Kim DH, Kim JM, Park SJ, Cai M, Jang DS, Ryu JH. The memory-ameliorating effects of Artemisia princeps var. orientalis against cholinergic dysfunction in mice. Am J Chin Med. 2012;40(5):993-1005.

 
40. Park SJ, Jung JM, Lee HE, Lee YW, Kim DH, Kim JM, Hong JG, Lee CH, Jung IH, Cho YB, Jang DS, Ryu JH. The memory ameliorating effects of INM-176, an ethanolic extract of Angelica gigas, against scopolamine- or A¥â(1-42)-induced cognitive dysfunction in mice. J Ethnopharmacol. 2012 Sep 28;143(2):611-20.
 
39. Hong JG, Kim DH, Lee CH, Park SJ, Kim JM, Cai M, Jang DS, Ryu JH. GSK-3¥â activity in the hippocampus is required for memory retrieval. Neurobiol Learn Mem. 2012 Sep;98(2):122-9.
 
38. Cai M, Phan PT, Hong JG, Kim DH, Kim JM, Park SJ, Liu X, Han JE, Park H, Choi JW, Ryu JH. The neuroprotective effect of eupatilin against ischemia/reperfusion-induced delayed neuronal damage in mice. Eur J Pharmacol. 2012 Aug 15;689(1-3):104-10.
 
37. Ha SK, Moon E, Ju MS, Kim DH, Ryu JH, Oh MS, Kim SY. 6-Shogaol, a ginger product, modulates neuroinflammation: a new approach to neuroprotection. Neuropharmacology. 2012 Aug;63(2):211-23.
 
36. Piers TM, Kim DH, Kim BC, Regan P, Whitcomb DJ, Cho K. Translational Concepts of mGluR5 in Synaptic Diseases of the Brain. Front Pharmacol. 2012;3:199.
 
35. Park SJ, Jung HJ, Son MS, Jung JM, Kim DH, Jung IH, Cho YB, Lee EH, Ryu JH. Neuroprotective effects of INM-176 against lipopolysaccharide-induced neuronal injury. Pharmacol Biochem Behav. 2012 May;101(3):427-33.
 
34. Park SJ, Kim DH, Jung JM, Kim JM, Cai M, Liu X, Hong JG, Lee CH, Lee KR, Ryu JH. The ameliorating effects of stigmasterol on scopolamine-induced memory impairments in mice. Eur J Pharmacol. 2012 Feb 15;676(1-3):64-70.
 
33. Kim DH, Kim JM, Park SJ, Cai M, Liu X, Lee S, Shin CY, Ryu JH. GABA(A) receptor blockade enhances memory consolidation by increasing hippocampal BDNF levels. Neuropsychopharmacology. 2012 Jan;37(2):422-33.
 
~ 2011
 
32. Kim DH, Park SJ, Kim JM, Jeon SJ, Kim DH, Cho YW, Son KH, Lee HJ, Moon JH, Cheong JH, Ko KH, Ryu JH. Cognitive dysfunctions induced by a cholinergic blockade and A¥â 25-35 peptide are attenuated by salvianolic acid B. Neuropharmacology. 2011 Dec;61(8):1432-40.(IF:4.114)
 
31. Cai M, Shin BY, Kim DH, Kim JM, Park SJ, Park CS, Won do H, Hong ND, Kang DH, Yutaka Y, Ryu JH. Neuroprotective effects of a traditional herbal prescription on transient cerebral global ischemia in gerbils. J Ethnopharmacol. 2011 Dec 8;138(3):723-30.
 
30. Hong JG, Kim DH, Park SJ, Kim JM, Cai M, Liu X, Lee CH, Ryu JH. The memory-enhancing effects of Kami-ondam-tang in mice. J Ethnopharmacol. 2011 Sep 1;137(1):251-6.
 
29. Kim JM, Kim S, Kim DH, Lee CH, Park SJ, Jung JW, Ko KH, Cheong JH, Lee SH, Ryu JH. Neuroprotective effect of forsythiaside against transient cerebral global ischemia in gerbil. Eur J Pharmacol. 2011 Jun 25;660(2-3):326-33.
 
28. Kim DH, Jung HA, Park SJ, Kim JM, Lee S, Choi JS, Cheong JH, Ko KH, Ryu JH. The effects of daidzin and its aglycon, daidzein, on the scopolamine-induced memory impairment in male mice. Arch Pharm Res. 2010 Oct;33(10):1685-90.
 
27. Jung HA, Jin SE, Choi RJ, Kim DH, Kim YS, Ryu JH, Kim DW, Son YK, Park JJ, Choi JS. Anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ChEs and BACE1. Life Sci. 2010 Sep 25;87(13-14):420-30.
 
26. Lee S, Kim DH, Lee DH, Jeon SJ, Lee CH, Son KH, Jung JW, Shin CY, Ryu JH. Oroxylin A, a flavonoid, stimulates adult neurogenesis in the hippocampal dentate gyrus region of mice. Neurochem Res. 2010 Nov;35(11):1725-32.
 
25. Lee S, Kim DH, Lee CH, Jung JW, Seo YT, Jang YP, Ryu JH. Antidepressant-like activity of the aqueous extract of Allium macrostemon in mice. J Ethnopharmacol. 2010 Sep 15;131(2):386-95.
 
24. Park SJ, Kim DH, Kim JM, Shin CY, Cheong JH, Ko KH, Ryu JH. Mismatch between changes in baicalein-induced memory-related biochemical parameters and behavioral consequences in mouse. Brain Res. 2010 Oct 8;1355:141-50.
 
23. Jung WY, Park SJ, Park DH, Kim JM, Kim DH, Ryu JH. Quercetin impairs learning and memory in normal mice via suppression of hippocampal phosphorylated cyclic AMP response element-binding protein expression. Toxicol Lett. 2010 Aug 16;197(2):97-105.
 
22. Kim JM, Kim DH, Park SJ, Park DH, Jung SY, Kim HJ, Lee YS, Jin C, Ryu JH. The n-butanolic extract of Opuntia ficus-indica var. saboten enhances long-term memory in the passive avoidance task in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Aug 16;34(6):1011-7.
 
21. Park SJ, Kim DH, Lee IK, Jung WY, Park DH, Kim JM, Lee KR, Lee KT, Shin CY, Cheong JH, Ko KH, Ryu JH.The ameliorating effect of the extract of the flower of Prunella vulgaris var. lilacina on drug-induced memory impairments in mice. Food Chem Toxicol. 2010 Jun;48(6):1671-6.
 
20. Kim DH, Yoon BH, Jung WY, Kim JM, Park SJ, Park DH, Huh Y, Park C, Cheong JH, Lee KT, Shin CY, Ryu JH.Sinapic acid attenuates kainic acid-induced hippocampal neuronal damage in mice. Neuropharmacology. 2010 Jul-Aug;59(1-2):20-30.
 
19. Kim DH, Jung WY, Park SJ, Kim JM, Lee S, Kim YC, Ryu JH. Anti-amnesic effect of ESP-102 on A¥â(1-42)-induced memory impairment in mice. Pharmacol Biochem Behav. 2010 Dec;97(2):239-48. (IF: 2.608)
 
18. Park SJ, Park DH, Kim DH, Lee S, Yoon BH, Jung WY, Lee KT, Cheong JH, Ryu JH. The memory-enhancing effects of Euphoria longan fruit extract in mice. J Ethnopharmacol. 2010 Mar 2;128(1):160-5
 
17. Kim DH, Kim JM, Park SJ, Lee S, Yoon BH, Ryu JH. Early-activated microglia plays a role in transient forebrain ischemia-induced neuronal cell proliferation in the dentate gyrus of mice. Neurosci Lett. 2010 May 14;475(2):74-9.
 
16. Kim DH, Hyun SK, Yoon BH, Seo JH, Lee KT, Cheong JH, Jung SY, Jin C, Choi JS, Ryu JH. Gluco-obtusifolin and its aglycon, obtusifolin, attenuate scopolamine-induced memory impairment. J Pharmacol Sci. 2009 Oct;111(2):110-6.
 
15. Lee S, Kim DH, Yoon SH, Ryu JH. Sub-chronic administration of rimonabant causes loss of antidepressive activity and decreases doublecortin immunoreactivity in the mouse hippocampus. Neurosci Lett. 2009 Dec 25;467(2):111-6
 
14. Jang S, Jung JC, Kim DH, Ryu JH, Lee Y, Jung M, Oh S. The neuroprotective effects of benzylideneacetophenone derivatives on excitotoxicity and inflammation via phosphorylated Janus tyrosine kinase 2/phosphorylated signal transducer and activator of transcription 3 and mitogen-activated protein K pathways. J Pharmacol Exp Ther. 2009 Feb;328(2):435-47.
 
13. Kim DH, Kim S, Jeon SJ, Son KH, Lee S, Yoon BH, Cheong JH, Ko KH, Ryu JH. Tanshinone I enhances learning and memory, and ameliorates memory impairment in mice via the extracellular signal-regulated kinase signalling pathway. Br J Pharmacol. 2009 Oct;158(4):1131-42.
 
12. Kim DH, Kim S, Jung WY, Park SJ, Park DH, Kim JM, Cheong JH, Ryu JH. The neuroprotective effects of the seeds of Cassia obtusifolia on transient cerebral global ischemia in mice. Food Chem Toxicol. 2009 Jul;47(7):1473-9.
 
11. Kim DH, Kim S, Jeon SJ, Son KH, Lee S, Yoon BH, Cheong JH, Ko KH, Ryu JH. The effects of acute and repeated oroxylin A treatments on Abeta(25-35)-induced memory impairment in mice. Neuropharmacology. 2008 Oct;55(5):639-47.
 
10. Cho KH, Oh JK, Jang YS, Jung JW, Oh HR, Park EK, Kim DH, Moon SK, Kim DH, Ryu JH. Combination drug therapy using edaravone and Daio-Orengedoku-to after transient focal ischemia in rats. Methods Find Exp Clin Pharmacol. 2008 Jul-Aug;30(6):443-50.
 
9. Shin JS, Hyun SY, Kim DH, Lee S, Jung JW, Choi JW, Ko KH, Kim JM, Ryu JH. Chronic hypoperfusion increases claudin-3 immunoreactivity in rat brain. Neurosci Lett. 2008 Nov 14;445(2):144-8.
 
8. Drever BD, Anderson WG, Riedel G, Kim DH, Ryu JH, Choi DY, Platt B. The seed extract of Cassia obtusifolia offers neuroprotection to mouse hippocampal cultures. J Pharmacol Sci. 2008 Aug;107(4):380-92.
 
7. Kim DH, Yoon BH, Kim YW, Lee S, Shin BY, Jung JW, Kim HJ, Lee YS, Choi JS, Kim SY, Lee KT, Ryu JH. The seed extract of Cassia obtusifolia ameliorates learning and memory impairments induced by scopolamine or transient cerebral hypoperfusion in mice. J Pharmacol Sci. 2007 Sep;105(1):82-93.
 
6. Kim DH, Jeon SJ, Jung JW, Lee S, Yoon BH, Shin BY, Son KH, Cheong JH, Kim YS, Kang SS, Ko KH, Ryu JH. Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in mice. Eur J Pharmacol. 2007 Nov 28;574(2-3):140-7.
 
5. Kim DH, Kim do Y, Kim YC, Jung JW, Lee S, Yoon BH, Cheong JH, Kim YS, Kang SS, Ko KH, Ryu JH. Nodakenin, a coumarin compound, ameliorates scopolamine-induced memory disruption in mice. Life Sci. 2007 May 1;80(21):1944-50.
 
4. Lee S, Kim DH, Jung JW, Oh JH, Park HJ, Park C, Huh Y, Cheong JH, Oh TH, Ryu JH. Schizandra chinensis and Scutellaria baicalensis counter stress behaviors in mice. Phytother Res. 2007 Dec;21(12):1187-92.
 
3. Kim DH, Jeon SJ, Son KH, Jung JW, Lee S, Yoon BH, Lee JJ, Cho YW, Cheong JH, Ko KH, Ryu JH. The ameliorating effect of oroxylin A on scopolamine-induced memory impairment in mice. Neurobiol Learn Mem. 2007 May;87(4):536-46.
 
2. Kim DH, Jeon SJ, Son KH, Jung JW, Lee S, Yoon BH, Choi JW, Cheong JH, Ko KH, Ryu JH. Effect of the flavonoid, oroxylin A, on transient cerebral hypoperfusion-induced memory impairment in mice. Pharmacol Biochem Behav. 2006 Nov;85(3):658-68.
 
1. Kim DH, Hung TM, Bae KH, Jung JW, Lee S, Yoon BH, Cheong JH, Ko KH, Ryu JH. Gomisin A improves scopolamine-induced memory impairment in mice. Eur J Pharmacol. 2006 Aug 7;542(1-3):129-35.
 
 
 
 
 
 
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