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Publications |
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• N Lee, K Youn, JH Yoon, B Lee, DH Kim, M Jun*. The Role of Fucoxanthin as a Potent Nrf2 Activator via Akt/GSK-3β/Fyn Axis against Amyloid-β Peptide-Induced Oxidative Damage. 2023. Antioxidants 12 (3), 629 |
• JH Yoon, K Youn, M Jun*. Discovery of pinostrobin as a melanogenic agent in cAMP/PKA and p38 MAPK signaling pathway. 2022. Nutrients 14 (18), 3713 |
• K Youn, CT Ho, M Jun*. Multifaceted neuroprotective effects of (-)-epigallocatechin-3-gallate (EGCG) in Alzheimer’s disease: An overview of pre-clinical studies focused on β-amyloid peptide. 2022. Food Science and Human Wellness 11 (3), 483-493 |
• E Cho, K Youn, H Kwon, J Jeon, WS Cho, SJ Park, SH Son, DS Jang, CY Shin, M Moon, M Jun, NJ Kim, DH Kim. Eugenitol ameliorates memory impairments in 5XFAD mice by reducing Aβ plaques and neuroinflammation. 2022. Biomedicine & Pharmacotherapy 148, 112763 |
• H Choi, JH Yoon, K Youn, M Jun*. Decursin prevents melanogenesis by suppressing MITF expression through the regulation of PKA/CREB, MAPKs, and PI3K/Akt/GSK-3β cascades. 2022. Biomedicine & Pharmacotherapy 147, 112651 |
• JH Yoon, K Youn, M Jun*. Protective effect of sargahydroquinoic acid against Aβ25–35-evoked damage via PI3K/Akt mediated Nrf2 antioxidant defense system. 2021. Biomedicine & Pharmacotherapy 144, 112271 |
• VL Truong, M Jun, WS Jeong. Phytochemical and over-the-counter drug interactions: Involvement of phase I and II drug-metabolizing enzymes and phase III transporters. 2021. Journal of Medicinal Food 24 (8), 786-805 |
• JH Yoon, N Lee, K Youn, MR Jo, HR Kim, DS Lee, CT Ho, M Jun*. Dieckol ameliorates Aβ production via PI3K/Akt/GSK-3β regulated APP processing in SweAPP N2a Cell. 2021. Marine Drugs 19 (3), 152 |
• J Yu, E Cho, H Kwon, J Jeon, JS Sin, JK Park, JS Kim, JW Choi, SJ Park, M Jun, YC Lee, JH Ryu, J Lee, M Moon, S Lee, JH Cho, DH Kim. Akt and calcium-permeable AMPA receptor are involved in the effect of pinoresinol on amyloid β-induced synaptic plasticity and memory deficits. 2021. Biochemical Pharmacology 184, 114366 |
• J Hwang, K Youn, G Lim, J Lee, DH Kim, M Jun*. Discovery of Natural Inhibitors of Cholinesterases from Hydrangea: In Vitro and In Silico Approaches. 2021. Nutrients 13 (1), 254 |
• JH Yi, H Kwon, E Cho, J Jeon, J Lee, YC Lee, JH Cho, M Jun, M Moon, JH Ryu, JS Kim, JW Choi, SJ Park, S Lee, DH Kim. REDD1 Is Involved in Amyloid β-Induced Synaptic Dysfunction and Memory Impairment. 2020. International Journal of Molecular Sciences 21 (24), 9482 |
• Y Ji, J Han, N Lee, JH Yoon, K Youn, HJ Ha, E Yoon, DH Kim, M Jun*. Neuroprotective effects of baicalein, wogonin, and oroxylin A on amyloid beta-induced toxicity via NF-κB/MAPK pathway modulation. 2020. Molecules 25 (21), 5087 |
• K Youn, JH Yoon, N Lee, G Lim, J Lee, S Sang, CT Ho, M Jun*. Discovery of sulforaphane as a potent BACE1 inhibitor based on kinetics and computational studies. 2020. Nutrients 12 (10), 3026 |
• K Youn, M Jun*. Geraniin Protects PC12 Cells Against Aβ25–35-Mediated Neuronal Damage: Involvement of NF-κB and MAPK Signaling Pathways. 2020. Journal of Medicinal Food 23 (9), 928-937 |
• J Hwang, K Youn, Y Ji, S Lee, G Lim, J Lee, CT Ho, SH Leem, M Jun*. Biological and Computational Studies for Dual Cholinesterases Inhibitory Effect of Zerumbone. 2020. Nutrients 12 (5), 1215 |
• HJ Park, H Kwon, JH Lee, E Cho, YC Lee, M Moon, M Jun, DH Kim, JH Jung, ¥â-Amyrin Ameliorates Alzheimer¡¯s Disease-Like Aberrant Synaptic Plasticity in the Mouse Hippocampus. 2020. Biomolecules & therapeutics 28 (1), 74 |
• J Han, Y Ji, K Youn, GT Lim, J Lee, DH Kim, M Jun*. Baicalein as a Potential Inhibitor against BACE1 and AChE: Mechanistic Comprehension through In Vitro and Computational Approaches. 2019. Nutrients 11 (11), 2694 |
• K Youn, S Lee M Jun*. Discovery of Nobiletin from Citrus Peel as a Potent Inhibitor of ¥â-Amyloid Peptide Toxicity. 2019. Nutrients 11 (11), 2648 |
• E Cho, M Cai, H Kwon, J Jeon, M Moon, M Jun, YC Lee, JH Yi, JH Ryu, DH Kim. Rubrofusarin inhibits A¥â aggregation and ameliorates memory loss in an A¥â-induced Alzheimer's disease-like mouse model. 2019. Food and Chemical Toxicology 132, 110698 |
• M Baek, MA Kim, YS Kwon, JS Hwang, TW Goo, M Jun, EY Yun. Effects of processing methods on nutritional composition and antioxidant activity of mealworm (Tenebrio molitor) larvae. 2019. Entomological Research 49 (6), 284-293 |
• K Youn, M Jun*. Biological evaluation and docking analysis of potent BACE1 inhibitors from Boesenbergia rotunda. 2019. Nutrients 11 (3), 662 |
• J Yu, H Kwon, E Cho, RH Kang, K Youn, M Jun, YC Lee, JH Ryu, DH Kim. The effects of pinoresinol on cholinergic dysfunction-induced memory impairments and synaptic plasticity in mice. 2019. Food and chemical toxicology 125, 376-382 |
• J. Lee, M. Jun*. Dual BACE1 and Cholinesterase Inhibitory Effects of Phlorotannins from Ecklonia cava-An In Vitro and in Silico Study. 2019. Marine drugs 17 (2), 91 |
• SR Lee, JY Mun, MS Jeong, HH Lee, YG Roh, WT Kim, MH Kim, J Heo, YH Choi, SJ Kim, HJ Cha, M Jun, SH Leem. Thymoquinone-Induced Tristetraprolin Inhibits Tumor Growth and Metastasis through Destabilization of MUC4 mRNA. 2019. International journal of molecular sciences 20 (11), 2614 |
•S. Lee, K. Youn, M. Jun*. Major Compounds of Red Ginseng Oil Attenuate A¥â25-35-induced Neuronal Apoptosis and inflammation by modulating MAPK/NF-¥êB pathway. Food & Function. 2018. 9 (8), 4122-4134 |
• K. Youn, J.-H. Park, S. Lee, S. Lee, J. Lee, E.-Y. Yun, W.-S. Jeong, M. Jun*. BACE1 inhibition by genistein: biological evaluation, kinetic analysis, and molecular docking simulation Journal of Medicinal Food. 2018 https://doi.org/10.1089/jmf.2017.4068 |
• K. Youn S. Lee, M. Jun*. Gamma-linolenic acid ameliorates A¥â-induced neuroinflammation through NF-¥êB and MAPK signalling pathways Journal of Functional Foods. 2018 42:30-37 |
• V.-L. Truong, M. Jun, W.-S. Jeong. Role of resveratrol in regulation of cellular defense systems against oxidative stress BioFactors. 2017 44:36-49 |
• S. Lee, K. Youn, W.-S. Jeong, C.-T. Ho, M. Jun*. Protective Effects of Red Ginseng Oil against A¥â25?35-Induced Neuronal Apoptosis and Inflammation in PC12 Cells International journal of molecular sciences. 2017 18:2218 |
• V.-L. Truong, M.J. Bak, C. Lee, M. Jun, W.-S. Jeong. Hair Regenerative Mechanisms of Red Ginseng Oil and Its Major Components in the Testosterone-Induced Delay of Anagen Entry in C57BL/6 Mice Molecules. 2017 22:1505 |
• K. Youn, Y. Yu, J. Lee, W.-S Jeong, C.-T. Ho, M. Jun*. Novel ¥â-Secretase (BACE1) Inhibitors from Citrus Peels. Nutrients. 2017 Sep 4:9(9). pii: E973. doi: 10.3390/nu9090973. |
• K. Youn, S. Lee, W.-S. Jeong, C.-T. Ho, M. Jun*. Protective Role of Corilagin on A¥â25?35-Induced Neurotoxicity: Suppression of NF-¥êB Signaling Pathway. Journal of Medicinal Food. 2016 19:901-911. |
• K. Youn, J.-H. Park, J. Lee, W.-S. Jeong, C.-T. Ho, M. Jun*. The Identification of Biochanin A as a Potent and Selective ¥â-Site App-Cleaving Enzyme 1 (Bace1) Inhibitor. Nutrients. 2016 8:637. |
• M.-J. Bak, V.-L. Truong, S.-Y. Ko, X.-N.-G Nguyen, M. Jun*, S.-G. Hong, J.-W. Lee, W.-S. Jeong. Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1?MKK4/7?JNK and p38 MAPK signaling pathways in HepG2 cells. Journal of Ginseng Research. 2016 40:423-430. |
• J. Song, M. Jun, M.-R. Ahn, O.-Y Kim. Involvement of miR-Let7A in inflammatory response and cell survival/apoptosis regulated by resveratrol in THP-1 macrophage. Nutrition Research and Practice. 2016 10:377-384. |
• V.-L Truong, S.-Y Ko, M. Jun, W.-S Jeong. Quercitrin from Toona sinensis (Juss.) M. Roem. Attenuates Acetaminophen-Induced Acute Liver Toxicity in HepG2 Cells and Mice through Induction of Antioxidant Machinery and Inhibition of Inflammation. Nutrients. 2016, 8:431. |
• M.-J. Bak, V.-L. Truong, S.-Y. Ko, X.-N.-G. Nguyen, P. Ingkasupart, M. Jun, J.-Y. Shin, W.-S. Jeong. Antioxidant and Hepatoprotective Effects of Procyanidins from Wild Grape (Vitis amurensis) Seeds in Ethanol-Induced Cells and Rats. International journal of molecular sciences. 2016 17:758. |
• H.-S. Bae, H.-J. Kim, D.-H Jeong, T. Hosoya, S. Kumazawa, M. Jun, O.-Y. Kim, S.-W. Kim, M.-R. Ahn. In Vitro and In Vivo Antiangiogenic Activity of Crowberry (Empetrum nigrum var. japonicum). Natural product communications. 2016 11:503. |
• K. Youn, J. Lee, C.-T. Ho, M. Jun*. Discovery of polymethoxyflavones from black ginger (Kaempferia
¡¡parviflora) as potential β-secretase (BACE1) inhibitors Journal of Functional Foods. 2016 14:1-11 |
• J. Lee, S. Yoon, G. Na, M. Jun, M.-R. Ahn, J. -K. Cha, O.Y. Kim. Fasting glucose is a useful indicator for
¡¡cerebrovascular risk in non- diabetic koreans: Association with oxidative stress and inflammation Clinica
¡¡l nutrition research. 2016 5:33-42 |
• 2012³â - 2015³â ³í¹® |
• 2011³â ÀÌÀü ³í¹® |
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Patents |
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• Àü¹Ì¶ó, À±±ÝÁÖ, À̼±¾Æ, À̽ÂÀº, À±Àº¿µ. °¥»ö°ÅÀú¸®·ÎºÎÅÍ ºÐ¸®ÇÑ ÈÇÕ¹°À» ÇÔÀ¯ÇÏ´Â ÅðÇ༺ ³úÁúȯ Ä¡·á¿ë ¾àÇÐÀû Á¶¼º¹° (µî·Ï¹øÈ£ 10-1890062) |
• Àü¹Ì¶ó, À±±ÝÁÖ. Ä«´Ù¸ð´ÑÀ» À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ½Å°æÁúȯ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (Ãâ¿ø¹øÈ£ 10-2018-0082734) |
• Àü¹Ì¶ó, À̽ÂÀº, Áö¿µ¼±, ÇÑÁø, À̳ª¿µ. Ç÷ηÎź´ÑÀ» À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ½Å°æÁúȯ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (Ãâ¿ø¹øÈ£ 10-2018-0136925) |
• Àü¹Ì¶ó, À¯À±Áø, À±±ÝÁÖ, À̼±¾Æ, ¹ÚÁöÇö. Çöó¹Ù³í À¯µµÃ¼¸¦ À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ³úÁúȯÀÇ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (µî·Ï¹øÈ£ 10-18014790000) |
• Àü¹Ì¶ó, À±±ÝÁÖ, À̼±¾Æ, ¹ÚÁöÇö. ºñ¿ÀÄ«´Ñ A¸¦ À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ³úÁúȯÀÇ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (µî·Ï¹øÈ£ 10-18014780000) |
• Àü¹Ì¶ó, À̼±¾Æ, À±±ÝÁÖ, ¹ÚÁöÇö. È«»ï¿ÀÀÏÀ» À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ½Å°æÁúȯ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (µî·Ï¹øÈ£ 10-1775267) |
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• Àü¹Ì¶ó, ¹ÚÁöÇö, À±±ÝÁÖ, À̼±¾Æ. À̼ÒÇöóº»À» À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ³úÁúȯÀÇ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (Ãâ¿ø¹øÈ£ 10-2016-0105502) |
• Àü¹Ì¶ó, À¯À±Áø, À±±ÝÁÖ, À̼±¾Æ, ¹ÚÁöÇö. Çöó¹Ù³í À¯µµÃ¼¸¦ À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ³úÁúȯÀÇ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹° (Ãâ¿ø¹øÈ£ 10-2016-0096753) |
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• Àü¹Ì¶ó, À̼±¾Æ, À±±ÝÁÖ, À±Àº¿µ, ȲÀç»ï, ±è¹Ì¾Ö, ¹é¹ÎÈñ. °¥»ö°ÅÀú¸®·ÎºÎÅÍ ºÐ¸®ÇÑ ½Å±Ô ÈÇÕ¹° ¹× ÀÌÀÇ ºÐ¸® ¹æ¹ý (Ãâ¿ø¹øÈ£ 10-2016-0041492) |
• Àü¹Ì¶ó, À̼±¾Æ, À±±ÝÁÖ, ¹ÚÁöÇö. È«»ï¿ÀÀÏÀ» À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ½Å°æÁúȯ ¿¹¹æ ¶Ç´Â Ä¡·á¿ë Á¶¼º¹°
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• Àü¹Ì¶ó, À±±ÝÁÖ, ±èÇý¸®, À̼±¾Æ, À±Àº¿µ, ȲÀç»ï. °¨¸¶¸®³î·»»êÀ» À¯È¿¼ººÐÀ¸·Î Æ÷ÇÔÇÏ´Â ÅðÇ༺ ½Å°æÁúȯÀÇ ¿¹¹æ
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